Mesothelioma Foundation Experts Can Answer Your Questions!

The Mesothelioma Applied Research Foundation's team of experts is available to answer your questions about mesothelioma, its symptoms and treatments as well as options available to you. This help is a free service. We are not a law firm. Read more about the Mesothelioma Applied Research Foundation.

TO GET HELP CALL: (877) End-Meso or (877) 363-6376 or fill out the form to the right to be contacted by us.

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National Mesothelioma Virtual Bank

The National Mesothelioma Virtual Tissue Bank is Coordinated by the Department of Biomedical Informatics at the University of Pittsburgh

Mesothelioma Tissue Resources Available for Your Research

The Mesothelioma Virtual Bank (NMVB) (http://www.mesotissue.org/) is funded by Center for Disease Control and Prevention (CDC) in association with National Institutes of Occupational Health and Safety (NIOSH) to provide mesothelioma biospecimens with clinical annotation to researchers.  The Meso Foundation made the NMVB possible due to the advocacy efforts of the Foundation's community.

The National Mesothelioma Virtual Bank (NMVB) collects and distributes mesothelioma tumor tissue and blood samples to the research community from consented patients. The specimens are stored with de-identified clinical data and that is made available for research. Investigators can search the study database to identify and request these materials via the NMVB website. NMVB is the largest and most accessible resource for biospecimens donated by mesothelioma patients.

Services:

- NMVB Database, allows researchers to search clinically annotated mesothelioma biospecimens and standardized clinical annotation structure to incorporate data from different data sources (https://www.data.mesotissue.org/mvb/home.seam).

- Specimens (Availability): Fresh Frozen, Fresh Frozen Paraffin Tissue, Blood Products, Tissue Microarray (https://mesotissue.org/tmas)

- Consultation and interpretive services are available by trained pathologists can provide assistance in staining, interpretation, scoring, and basic statistical analysis. In addition, consultation and planning for large-scale studies are available.

For further details: Please visit www.mesotissue.org and contact us via e-mail (https://mesotissue.org/contact)

All researchers may apply for the NMVB mesothelioma tissue resources
(academic or commercial, US or foreign)

SEARCH THE ONLINE PUBLIC DATABASE (https://www.data.mesotissue.org/mvb/home.seam)

Investigators can search to determine whether the resource has the mesothelioma tissue samples they need for their research. Search fields include:

Stage of Disease Treatment Received
Histopathologic Type Recurrence Info
Histopathologic Grade Metastatic Disease
Availability of Normal Tissue Follow-up Time
Vital status, Nodal status

 *(User must use Internet Explorer 5.5 or higher to view database)

Consultation and Interpretive Services:  Assistance is available from trained NMVB pathologists. The NMVB can provide consultative assistance in staining interpretation, scoring, and basic statistical analysis of NMVB TMA on a collaborative basis. These services are available from trained pathologists familiar with mesothelioma tissue microarray and immunohistochemical staining interpretation. In addition, consultation and planning for large scale studies are also available. For further details, please e-mail us at asknmvb@pitt.edu.

Currently Available Resources:  (Further detail is available on the NMVB website)

NMVB Biospecimen Availability:
The resource has over 600 annotated cases (900 biospecimens including paraffin, fresh frozen, blood and DNA samples).

Tissue Microarray (TMA):
The NMVB is now pleased to announce the availability of slides from mesothelioma TMA with associated clinical data.

Currently Available TMA Constructed Based On: Samples from 40 patients have been incorporated: 36 patients have tissue cores from the primary lesion only, 3 patients have tissue cores from a metastatic lesion only, and 1 patient has tissue cores from both the primary and metastatic lesions. Of the patients with available clinical annotation, 97% are male and 3% are female, and racial breakdown is as follows: 57% white, 3% black, and 39% unknown.

The information provided for each case on the array includes over 25 data elements including: age at diagnosis, race, asbestoses exposure, tumor size, histologic type, TNM staging, grade, and vital status.


An application form for paraffin or frozen tissues and TMA is available at https://www.mesotissue.org/node23.
Please e-mail asknmvb@pitt.edu if you have any questions about our TMA or our large repository of paraffin-embedded and fresh-frozen mesothelioma tissue samples.