Click here to see the full list of the 2008 Symposium presentations.
Session 1: Peritoneal Mesothelioma - Video 1 of 3 - Taub
Dr. Robert N. Taub is currently the Vivian and Seymour Milstein Family Professor of Clinical Medicine at Columbia University College of Physicians and Surgeons, New York, NY. Dr Taub is the Founder and Director of the Mesothelioma Center at Columbia University Medical Center and an Attending Oncologist in the Division of Medical Oncology. He is a Fellow of the American College of Physicians, board certified in internal medicine, oncology, hematology and immunology. He has published 143 papers in peer reviewed journals. He is a member of the American
Society of Clinical Investigation and the recipient of awards from The American Cancer Society, The Leukemia Society of America, the Israel Cancer Research Fund, and the Mount Sinai Hospital. NY. Dr Taub has been a member of the
Scientific Advisory Board of the Mesothelioma Applied Research Foundation and has participated each year in the Foundations’ peer review grants program. He has been a featured speaker at many of the Foundation’s Symposia.
Dr. Taub’s current research interests include the cell biology and molecular profiling of peritoneal and pleural mesothelioma and their management with intracavitary chemotherapy and novel systemic agents.
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Session 1: Peritoneal Mesothelioma - Video 2 of 3 - Pingpank
Dr. Pingpank is the Head of the Surgical Metabolism Section of the Surgery Branch of the NCI, in Bethesda Maryland. He is the principal investigator on a phase II trial examining the utility of cytoreduction and intraperioneal chemoperfusion in the treatment of primary peritoneal mesothelioma.
Dr. Pingpank's research program is focused on the role of signal transduction pathways in the pathogenesis of malignant peritoneal mesothelioma, and which additionally may serve as therapeutic targets.
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Session 1: Peritoneal Mesothelioma - Video 3 of 3 - Alexander
Dr. Alexander is an internationally recognized surgical oncologist and clinical researcher. He treats cancer patients at the University of Maryland Marlene and Stewart Greenebaum Cancer Center and is associate chairman for clinical research in the University of Maryland Department of Surgery.
Dr. Alexander is recognized for developing innovative techniques to treat patients with malignant peritoneal mesothelioma. His clinical research program has been instrumental in establishing that operative cytoreduction and intra-operative hyperthermic perfusion with chemotherapy is associated with durable clinical benefit. His laboratory is focused on identifying new therapeutic interventions based on elucidating the molecular profiles and cellular pathways that are activated in peritoneal mesothelioma.
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Session 2: Pleural Mesothelioma Surgical Options - Video 1 of 2 - Flores
Raja Flores was born and raised in New York. He attended college at New York University, and medical school at Albert Einstein College of Medicine. He did his cardiothoracic surgery training at the Brigham and Women’s Hospital of Harvard Medical School. He has been an attending thoracic surgeon at Memorial Sloan Kettering Cancer Center in New York for approximately seven years using surgical techniques to cure lung cancer, esophageal cancer, and malignant mesothelioma. He also obtained masters in biostatistics and clinical research methods at Columbia University. And has put together several sentinel papers in mesothelioma including the largest single center experience and the largest series
comparing Extrapleural Pneumonectomy to Pleurectomy Decortication. He continues to maintain a database of over 1,000 patients with mesothelioma.
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Session 2: Pleural Mesothelioma Surgical Options - Video 2 of 2 - Kratzke
Dr. Kratzke is currently an Associate Professor of Medicine at the University of Minnesota Medical School in the Section of Hematology, Oncology, and Transplantation. In 2004, Dr. Kratzke was established as the first holder of the John Skoglund Chair in Lung Cancer Studies at the University of Minnesota.
Dr. Kratzke’s research has centered around molecular abnormalities in lung cancer and mesothelioma, focusing primarily on cell cycle regulator genes and their loss of function in cancer. He has studied gene replacement therapy for mesothelioma using murine models resulting in curative treatment in the animal model. Dr. Kratzke has been an invited speaker on mesothelioma at International Mesothelioma Interest Group biennial meetings, as well as the biennial meetings of the International Association for the Study of Lung Cancer.
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Session 3: Emerging Therapies in Mesothelioma - Video 1 of 3 - Tsao
Dr. Anne S. Tsao is an Assistant Professor in the Department of Thoracic/Head & Neck Medical Oncology at the University of Texas M.D. Anderson Cancer Center. Dr. Tsao’s clinical and translational research is focused on identifying new therapeutic targets and developing novel strategies for the treatment of aerodigestive cancers and mesothelioma. Her mesothelioma research efforts have recently identified Src kinase as a new target for therapy (Molecular Cancer Therapeutics) and have also shown that N-cadherin is upregulated in this disease (AACR 2008, ASCO 2008). Dr. Tsao is the principle investigator of six active mesothelioma clinical trials at M.D. Anderson Cancer Center.
She has also been extremely successful with numerous awards and publications. She has received an ASCO Merit Award, M.D. Anderson Achievement in Research Award, ASCO Young Investigator Award, ASCO Career Development Award, NIH Clinician Scientist K12 Award, and Head and Neck SPORE Career Development Award. She has several first author publications in Journal of Clinical Oncology, CA Cancer, Cancer Epidemiology, Biomarkers & Prevention (CEBP), Journal of Thoracic Oncology, Cancer, and Molecular Cancer Therapeutics. Dr. Tsao serves on the SWOG Mesothelioma Steering Committee and is on the Scientific Board of the American Radium Society. She lectures on both a national and international level on novel therapies.
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Session 3: Emerging Therapies in Mesothelioma - Video 2 of 3 - Mutti
Since 1999 Dr. Luciano Mutti M.D, Ph.D has been the Chief of the Dept of Medicine and Head of the Lab of Clinical Oncology of Vercelli General Hospital in Italy. He is the Chair of the Scientific Committee of the Buzzi Foundation for research on Mesothelioma and of the Italian Group for the Research and therapy of Mesothelioma (GIMe), Italian Director of the International Mesothelioma Interest Group (IMIG) and expert leader of the European Respiratory Society (ERS) for Chemotherapy and novel therapies for Mesothelioma
Dr. Mutti began his research investigating the immune response against mesothelioma cells and over the last years has been coordinating a multidisciplinary team-oriented approach to mesothelioma ranging from molecular epidemiology to cell signaling transduction and novel translational therapies for this tumor. (Imatinib Mesylate, Bortezomib, Antiangiogenics and anti-CTLA4).
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Session 3: Emerging Therapies in Mesothelioma - Video 3 of 3 - Albelda
Dr. Albelda’s research interests focus on developing novel approaches to the treatment of mesothelioma and lung wall cancers, with special emphasis on gene therapy. His clinical interests are primarily in thoracic oncology. In 1992, he co-founded a translational “Thoracic Oncology Research Laboratory” aimed at moving research from “bench to bedside”. He has led an NCI-funded Program Project aimed at developing new treatments for mesothelioma for the past 12 years.
His initial research in gene therapy used the “suicide gene” Herpes Simplex Thymidine Kinase and led to a series of clinical trials for patients with mesothelioma. More recently, the lab has refocused on immuno-gene therapy using the cytokine interferon-beta. Clinical trials of Adenovirus-Interferon-beta in patients with mesothelioma and metastatic pleural disease are ongoing, along with studies in the laboratory to examine mechanisms and improvement of these treatment strategies.
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Session 4: Optimizing Patient Care in Mesothelioma - Video 1 of 1 - Hesdorffer
Mary Hesdorffer received her undergraduate degree at the College of New Rochelle in NY and went on to receive her Masters of Science at the same institution. She is fully credentialed as a Nurse Practitioner and has spent the past 11 years actively treating patients with mesothelioma. Mary has an expertise in the development and implementation of clinical trials. She has published in peer reviewed journals and has lectured nationally on the topics pertaining to mesothelioma with particular emphasis on clinical trials as well as symptom and disease management, she is well known to the Foundation's community having attended and spoken at many of our symposiums. Mary is passionate in her commitment to the treatment and management of this disease and hopes to increase awareness of the need to advance the science that will lead to a cure. She is available via phone or email to assist patients and caregivers as they move from chaos to control of this new situation they find themselves thrust into.
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Session 5: Scientific Advances in Mesothelioma Research - Video 1 of 1 - Hassan
Dr. Hassan, is an Investigator and Chief of the Solid Tumor Immunotherapy Section in the Laboratory of Molecular Biology at the National Cancer Institute. Dr. Hassan is a medical oncologist whose laboratory and clinical research is focused on developing novel therapies for the treatment of mesothelioma. Work done by him and his collaborators has shown that mesothelin, a tumor antigen which was discovered at the NCI, is a useful target for tumor-specific therapy of malignant mesothelioma. His group is presently conducting clinical trials of three different agents targeting mesothelin namely, SS1P an anti-mesothelin immunotoxin, MORAb-009 a chimeric anti-mesothelin monoclonal antibody and CRS- 207 a mesothelin tumor vaccine.
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Symposium Gala: Address by Keynote Speaker - Lexi Miletto
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Symposium Gala: Hope Builder Award 2008 - Congresswoman Lois Capps
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Symposium Gala: Pioneer Award 2008 - Dr. Harvey Pass
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Symposium Gala: Volunteer of the Year Award 2008 - Nancy Buszinski and June Breit
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Symposium Trailer
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