Pleural Mesothelioma Treatment
Primary Surgical Procedures in the Treatment of Pleural MesotheliomaThere are two primary surgical protocols used in treating pleural mesothelioma:
Assessing the Risk of surgeryBefore these two mesothelioma treatment procedures are performed, a series of tests must be performed to determine that the patient can tolerate the rigors of the surgery.
Assessing the patients tolerance for pleural mesothelioma surgery includes:
Surgical Treatment ChallengesDespite the pre-surgical work up many patients are found to have unresectable disease and the operation is abandoned To undergo surgery of this magnitude, a patient needs to have a healthy heart, a viable second lung and, in the case of adjuvant chemotherapy during surgery, strong kidney functions and a healthy liver. Age, general health and the condition of the respiratory system, histology, extent of disease at the time of surgery all have a direct bearing on the outcome of the surgery and ensure that morbidity and mortality rates are kept as low as possible. There is great controversy as to which procedure should be offered to eligible patients and much discussion is taking place among the experts in this disease in trying to determine what prognostic variable make a particular patient more likely to benefit from surgery. Patients are therefore encouraged to seek an opinion from both a medical oncologist and a surgical oncologist who have developed an expertise in mesothelioma treatment. Full discussion of risks vs. benefits need to be addressed at these consultations plus ample time for questions to be asked.
To learn more about the side effects and risks involved in surgically treating pleural mesothelioma, please visit the Surgical Risks and Side Effects page.
Searching for more Resources on the Surgical Treatment of Pleural Mesothelioma? Please browse the list of resources below:
Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: Results in 663 patients.
A phase I study of extrapleural pneumonectomy and intracavitary intraoperative hyperthermic cisplatin with amifostine cytoprotection for malignant pleural mesothelioma.
Multicenter phase II trial of neoadjuvant pemetrexed plus cisplatin followed by extrapleural pneumonectomy and radiation for malignant pleural mesothelioma.
Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma.