In this episode of MesoTV, Julie sits down with Dr. Raffit Hassan and Dr. David Schrump from the Center for Cancer Research at National Institutes of Health and National Cancer Institute to discuss BAP1 and how it relates to mesothelioma.
BAP1 stands for BRCA1-associated protein 1. It’s a gene that makes a protein responsible for regulating things like cell growth, DNA repair, and cell death. In simple terms, it acts as a tumor suppressor—helping prevent cells from growing out of control. If the BAP1 gene is mutated or lost cells can accumulate DNA damage and tumors can develop more easily. People with inherited BAP1 mutations have a higher risk of developing mesothelioma—even with lower levels of asbestos exposure.
If you have any questions about BAP1 and how it relates to mesothelioma, please reach out to our Director of Patient Services, Julie White, at [email protected].
Our Sponsors
MesoTV is a program by the Mesothelioma Applied Research Foundation. This program is made possible by our generous sponsors: Belluck Law, Dean Omar Branham Shirley, LLP; Maune Raichle Hartley French & Mudd, LLC (MRHFM); The Gori Law Firm; Merck; Early Luccarelli Sweeney & Meisenkothen, LLC; AstraZeneca
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